The Efficacy of Computerized Cognitive Remediation Therapy for Chronic Schizophrenia
Status:
Unknown status
Trial end date:
2021-03-31
Target enrollment:
Participant gender:
Summary
The study group received antipsychotic drugs combined with Computerized Cognitive Remediation
Therapy (CCRT) for 4 times/week for 45 minutes each time. The control group only received
antipsychotic drugs. For a total of 12 weeks. Brain Derived Neurotrophic Factor (BDNF) and
Tropomyosin-related kinase B (Trk B) genes in peripheral blood were detected in both groups
before and after treatment. Clinical symptoms and executive function assessment were
performed in both groups before and after treatment. The relevance of genes and their effects
on downstream protein expression levels led to a molecular genetic mechanism for the efficacy
of Computerized Cognitive Remediation Therapy (CCRT) .