Overview

The Efficacy of JS001 Combined With Chemotherapy in Patients With Locally Advanced Colon Cancer

Status:
Recruiting
Trial end date:
2026-06-01
Target enrollment:
Participant gender:
Summary
Colon cancer is one of the most lethal malignancies, and colorectal cancer ranks the fifth leading cause of tumor-related mortality in China. FOLFOX is the recommended adjuvant/ neoadjuvant treatment for advanced colon cancer. JS001, as the first Chinese produced anti-PD-1 monoclonal antibody, has been approved by CFDA. This study aims to assess the safety and efficacy of JS001 in combination with FOLFOX as adjuvant/neoadjuvant treatment for patients with locally advanced colon cancer.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Xiangya Hospital of Central South University
Treatments:
Antibodies
Antibodies, Monoclonal
Antineoplastic Agents, Immunological