The Efficacy of N-acetylcysteine Versus Placebo for the Treatment of Metamphetamine Withdrawal Symptoms
Status:
Completed
Trial end date:
2020-12-30
Target enrollment:
Participant gender:
Summary
Up to date, no approved medications are available for the treatment of methamphetamine
addiction. Recently, N-acetylcysteine is recently being studied for methamphetamine
withdrawal.
N-acetylcysteine, is a drug that has been long used as a mucolytic. Recent studies
investigate the use of N-acetylcysteine in cocaine and withdrawal symptoms by its effect on
restoring glutamate homeostasis in nucleus accumbens. Up to date, there has been 2 pilot
study investigating the efficacy of N-acetylcysteine for methamphetamine dependence.
The present study is aimed to confirm the efficacy and safety of N-acetylcysteine in the
treatment of methamphetamine withdrawal symptoms.