The Efficacy of Periarticular Single Drug Compared With Multimodal Drug Injection in Controlling Pain After TKA

• Status: Completed
• Trial end date: 2014-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the periarticular multimodal drug injection has more efficacy for controlling pain after TKA than single anaesthetic drug injection.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Thammasat University
• Treatments: Anesthetics; Bupivacaine; Levobupivacaine

Criteria

Inclusion Criteria:

• primary osteoarthritis of the knee who undergoing unilateral primary total knee arthroplasty

• age 50-85 years old

Exclusion Criteria:

• unable to perform spinal anaesthesia

• history of drug allergies; local anaesthesia, Non-steroidal anti-inflammatory drugs, morphine, epinephrine

• cognitive function impairment

• renal impairment (creatinine clearance < 30 mL/min)

• liver impairment, gastrointestinal bleeding