The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis

• Status: Unknown status
• Trial end date: 2019-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficacy of Si-Ni-Tang (a Chinese Herbal Formula documented in Shang Han Lun) in treating severe sepsis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Guangdong Provincial Hospital of Traditional Chinese Medicine

Criteria

Inclusion Criteria:

• Severe sepsis (according to American college of chest Physicians/ Society of Critical Care Medicine (ACCP/SCCM) criteria)

• Informed consent provided by patients or legally authorized representative

• Yin syndrome in syndrome differentiation (according to principles of traditional Chinese medicine (TCM) syndrome differentiation)

Exclusion Criteria:

• Pregnant or nursing female

• Subject receiving immunosuppressive or immunoenhancement therapy in the past 3 months

• Patients with known or suspicious autoimmune diseases

• Patients not expected to survive 28 days due to end-stage disease or other uncorrectable medical condition

• Fasting subjects

• Known or suspicious allergy to any ingredient of Si-Ni-Tang

• Patients not expected to survive 5 days for various reasons