The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients

• Status: Completed
• Trial end date: 2007-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the efficacy of the α-adrenergic antagonist tamsulosin in the treatment of adult emergency department (ED) patients with ureteral colic secondary to lower ureteral calculus. We hypothesize that there will be no difference in outcomes for subjects treated with and without tamsulosin.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Maine Medical Center; MaineHealth
• Collaborator: Maine Medical Center Mentored Research Committee
• Treatments: Ibuprofen; Oxycodone; Tamsulosin

Criteria

Inclusion Criteria:

• 18 years of age or older;

• able to read, write, and speak English;

• able to use the NRS pain scale; and

• computed tomography diagnosed single lower ureteral calculus

Exclusion Criteria:

• allergy or sensitivity to the study drug (tamsulosin hydrochloride [Flomax]);

• sulfa/sulfonamide allergy;

• inability to provide informed consent;

• lithiasis of the ureteral intramural tract;

• acute or chronic renal failure;

• fever;

• presence of multiple ureteral stones;

• peptic ulcer disease;

• liver failure;

• concomitant treatment with alpha-lytic drugs, calcium antagonists, nitrates, or vardenafil (Levitra);

• pregnancy;

• breastfeeding; or

• a history of urinary surgery or endoscopic treatment.