The Efficacy of Using Pentoxifylline in Patients Undergoing Breast Cancer Surgery

• Status: Recruiting
• Trial end date: 2024-06-30
• Target enrollment: 0
• Participant gender: Female

Summary

The goal of this clinical trial is to assess the efficacy of pentoxifylline in reducing post surgical complications for breast cancer patients undergoing breast cancer surgery. It aims to evaluate the efficacy of pentoxifylline on postoperative pain and wound healing.

Participants will take oral pentoxifylline then post surgical oral pentoxifylline three times per day for 2 weeks. The researchers will compare the difference in pain score and wound healing relative to the control group.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Pentoxifylline

Criteria

Inclusion Criteria:

1. Adult female patients aged 18 to 65 years

2. Patients completed neoadjuvant chemotherapy cycles and scheduled for breast cancer surgery.

Exclusion Criteria:

1. Patients on treatment regimen of phosphodiesterase inhibitors

2. Patients who are taking antiplatelet or anticoagulant treatment

3. Patients who are allergic to phosphodiesterase inhibitors

4. History of recent hemorrhagic events

5. Active peptic ulcer

6. History of psychological problems

7. History of chronic pain management

8. Pregnancy or breastfeeding