Overview

The Efficacy of Zoledronic Acid in Modic Changes-related Low Back Pain (LBP)

Status:
Completed
Trial end date:
2012-03-01
Target enrollment:
Participant gender:
Summary
Modic changes are associated with low back pain (LBP) both in clinical and general population-based samples. Type I changes are regarded as more likely to be painful than type II changes. Several studies suggest that type I changes are inflammatory in nature.
Phase:
Phase 2
Details
Lead Sponsor:
University of Oulu
Collaborator:
Novartis Pharmaceuticals
Treatments:
Diphosphonates
Zoledronic Acid