The Efficacy of the Traditional Chinese Medicine Fangji Huangqi Pill Combined With Mobic on Active Knee Osteoarthritis

• Status: Unknown status
• Trial end date: 2018-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Knee osteoarthritis (KOA) is known as degenerative joint disease, which is the most common form of arthritis and the leading cause of disability, loss of function and pain worldwide. Effective therapy to manage RA is still lack at present. Fangji Huangqi pill (FHP) is a Chinese medicine which has been widely used in treating KOA in China for hundreds of years to relieve pain, reduce swelling and protect the affected joints from further degeneration. However, no certain evidence to show the effect of FHP for the management of active KOA.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cui xuejun; Shanghai University of Traditional Chinese Medicine
• Treatments: Meloxicam

Criteria

Inclusion Criteria:

• Meet the diagnostic criteria for knee osteoarthritis (American College of Rheumatology criteria)

• Grade 0-3 on the Kellgren-Lawrence grading system

• No serious medical history

• No known drug allergies

• No steroids, glucosamine, chondroitin sulfate, sodium hyaluronate before Fangji Huangqi pill treatment within 1 month

Exclusion Criteria:

• Combined with other disease such as rheumatoid arthritis, lupus arthritis and et. al

• Grade 4 on the Kellgren-Lawrence grading system

• Allergy to study drug

• Participating in other clinical trial

• Unwilling to give informed consent