The Electroretinogram in Healthy and Glucose Intolerant Young Men

• Status: Completed
• Trial end date: 2010-06-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose is to investigate the electroretinogram (ERG) in young, healthy men in the normoglycaemic and hyperglycaemic state before and after intervention with corticosteroids treatment, high calorie diet and exercise restraint.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Glostrup University Hospital, Copenhagen
• Treatments: Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• Caucasians without type 2 diabetes mellitus

• Normal OGTT (75 g glucose dissolved in 250 mL water) according to WHO's criteria

• BMI 20-30

• Haemoglobin > 8,0 mM

Exclusion Criteria:

• Nephropathy (s-creatinin > 130 µM or albuminuria)

• Relatives (parents or sibling with T2DM)

• Medical treatment which cannot be paused for 12 hours