The Feasibility of Dexmedetomidine for Awake Fiberoptic Nasal Intubation

• Status: Unknown status
• Trial end date: 2009-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to evaluate the feasibility of dexmedetomidine infusion for oral cancer patients undergoing awake fiberoptic nasal intubation. We hypothesized that a loading dose of intravenous dexmedetomidine before awake fiberoptic nasal intubation for oral cancer patients undergoing general anesthesia will provide adequate sedation and analgesia without respiratory depression and upper airway obstruction.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital
• Treatments: Dexmedetomidine; Propofol

Criteria

Inclusion Criteria:

• Head and neck cancer patients with limited mouth opening

• Undergoing awake fiberoptic nasal intubation for elective surgery

Exclusion Criteria:

• a history of severe bradycardia

• any type of A-V block in EKG

• heart failure

• liver cirrhosis

• thrombocytopenia

• coagulopathy