The Feasibility of Different Doses of Etomidate Admixed With Propofol in Induced Abortion: A Randomized, Double Blind Controlled Trial

• Status: Unknown status
• Trial end date: 2015-02-01
• Target enrollment: 0
• Participant gender: All

Summary

To explore the feasibility of different doses of etomidate admixed with propofol in induced abortion: a randomized, double blind controlled trial.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Third Affiliated Hospital of Zhengzhou University
• Treatments: Etomidate; Pentazocine; Propofol

Criteria

Inclusion Criteria:

• Aged between 20 and 35 years

• American Society of Anesthesiology (ASA) Physical Status: Ⅰ or Ⅱ

• Singleton pregnancy and the gestational period is 6 to 8 weeks

• Expected operation duration is within 60 minutes

• The body weight should be within 15% around the standard weight

• Signed informed consent form

Exclusion Criteria:

• Serious cardiac, cerebral, liver, kidney, lung, endocrine disease

• Upper respiratory infections within 4 weeks

• Long use of hormone or history of adrenal suppression

• History of use of glucocorticoids, aprotinin or immunosuppressant

• Manifestation of immunodeficiency

• History of use of sedatives or opiates

• Needs of Neuromuscular blocker (except intubation)

• Allergy to trial drug or other contraindication

• Pregnant or breast-feeding women

• Attended other trial past 30 days