Overview

The GABAergic Inhibitory System in Drug Resistant Epilepsy

Status:
COMPLETED
Trial end date:
2024-04-01
Target enrollment:
Participant gender:
Summary
This study aims to investigate the effect of lovastatin on neurotransmission and neuroinflammation in patients with temporal lobe onset drug resistant epilepsy. Structure: (1) Visit 1: 3 consecutive days of physiologically probing drug/placebo intake, (2) Visit 2: Outcome measures and additional evaluations in the day after the last drug/placebo intake, (3) Washout period of 4 weeks, (4) 3 consecutive days of drug/placebo intake, (5) Visit 3: Outcome measures and additional evaluations in the day after the last placebo/drug intake.
Phase:
NA
Details
Lead Sponsor:
University of Coimbra
Treatments:
Lovastatin