Atorvastatin is a statin that significantly decreases LDL level. At 10 mg/day, atorvastatin
increases HDL level by 4-5%. At 80 mg/day, atorvastatin does not increase HDL level. However,
atorvastatin is more protective at 80 mg/day than at 10 mg/day. This is due to a better
reduction in LDL level at 80 mg, but we also think that 80 mg/day of atorvastatin is superior
to 10 mg/day in improving the QUALITY of HDL, such as improving HDL particle number and
function (better anti-oxydant activity)
Phase:
Phase 4
Details
Lead Sponsor:
Hotel Dieu de France Hospital
Collaborators:
Nouvelle Société Française d'Athérosclérose Pfizer