The HIT-TRAP Trial

• Status: Unknown status
• Trial end date: 2005-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Randomised, double blind trial in non-intensive care trauma patients comparing unfractionated heparin (UFH) or low-molecular-weight heparin (LMWH) in heparin-induced thrombocytopenia (HIT).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Medicine Greifswald
• Collaborator: Novartis
• Treatments: Calcium heparin; Certoparin; Dalteparin; Heparin; Heparin, Low-Molecular-Weight

Criteria

Inclusion Criteria:

• trauma-surgical patient

• consent given

• minimum age 18

• expected inpatient period at least 7 days

• need for thrombosis prophylaxis with heparin

Exclusion Criteria:

• intolerance of one of the study drugs

• malignancy with life expectancy < 3 months

• pregnancy/lactation

• drug or alcohol abuse

• fibrinolytic therapy

• need for extracorporal circulation (e.g. cardiopulm. bypass, hemodialysis) at study entry

• participation in another clinical trial within 30 days prior to intended inclusion