The HOME Trial: Hyperinsulinaemia: the Outcome of Its Metabolic Effects, a Randomized Controlled Trial
Status:
Completed
Trial end date:
2002-10-01
Target enrollment:
Participant gender:
Summary
The HOME-trial is a prospective, randomized controlled trial. The purpose of this study is to
investigate the effects of metformin HCL in patients with type 2 diabetes mellitus
intensively treated with insulin on the quality of the metabolic control of diabetes, the
daily dose of insulin, the lipid profile, the blood pressure, the incidence / progression of
microvascular and macrovascular complications, and on the qualify of life (Diabetes Health
Profile). Early results had been published in Diabetes Care, December 2002, pages 2133-2140.