Overview
The Hemostatic and Hemodynamic Effects of Adrenaline During Endoscopic Sinus Surgery
Status:
Unknown status
Unknown status
Trial end date:
2010-04-01
2010-04-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Obtaining adequate hemostasis is crucial during endoscopic sinus surgery. Submucosal injection of local anaesthetic containing adrenaline has frequently been used to improve surgical milieu. However, injection of adrenaline has potential side effects including tachycardia, hypertension as well as inducing arrhythmia. The aim of this randomized clinical trial is to assess the hemodynamic and hemostatic effects of two different concentrations of adrenaline in local anaesthetic used during endoscopic sinus surgery.Phase:
Phase 3Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
University of TorontoTreatments:
Epinephrine
Epinephryl borate
Hemostatics
Lidocaine
Racepinephrine
Criteria
Inclusion Criteria:- recurrent acute sinusitis, chronic sinusitis, or nasal polyposis
Exclusion Criteria:
- bleeding disorders, under age of 18, history of cardiac disease or on antihypertensive
medications