The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain
Status:
Unknown status
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
Vitamin D3 is produced in the skin following exposure to UVB light from the sun or artificial
sources, and occurs naturally in a small range of foods.More recently, several reports
underlined the impact of vitamin D on the prevalence and consequences of inadequate vitamin D
intake and the research supporting its benefits for alleviating chronic musculoskeletal pain
and fatigue syndromes in outpatients. Experts have recommended that vitamin D inadequacy
should be addressed in all patients with bone or joint pain, myalgia, fibromyalgia, or
chronic fatigue syndrome. It appears that soothing the daily musculoskeletal pain by
supplementation of vitamin D may be a simple, well tolerated, and cost-effective modality.
Aim of study:
To study the potential therapeutic effects of vitamin D supplementation on patients with
persistent musculo-skeletal pain. Clinicalparameters, visual analog score,short form McGill
Pain Questionnaire,patient global perceived effect, quality of life assessed by SF-36
Questionnaire and laboratory parameters, the levels of 25 OH-Vitamin D, CRP, IL-6, IL-8, TNF
and prostaglandin E will be assessed.