The Impact of Immunostimulating Nutrition on the Outcome of Surgery

• Status: Completed
• Trial end date: 2005-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study was to assess the clinical effect of immunostimulatory enteral and parenteral nutrition in patients undergoing resection for gastrointestinal cancer. 205 subjects were randomly assigned into four study groups, standard and immunostimulating, enteral and parenteral. The study was designed to test the hypothesis that immunonutrition and enteral nutrition would reduce the incidence of infectious complications following upper gastrointestinal surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Jagiellonian University

Criteria

Inclusion Criteria:

• resectable gastric or pancreatic cancer

• age between 18 and 80 years,

• Karnofsky performance status score of 80 or more,

• adequate organ function

Exclusion Criteria:

• unresectable gastric or pancreatic cancer

• patients requiring preoperative nutritional support,

• disseminated tumors,

• serious comorbidities (American Society of Anesthesiologists risk class of 4 or 5),

• renal or liver failure were excluded