The Impact of N-Acetylcysteine on Volumetric Retention of Autologous Fat Graft for Breast Asymmetry Correction

• Status: Unknown status
• Trial end date: 2018-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to assess the effect of new tumescent solution for liposuction containing N-Acetylcysteine (Pietruski solution) on the autologous fat graft volumetric retention used for healthy women breast asymmetry correction by means of lipofilling.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre of Postgraduate Medical Education
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

• Female

• Age 18-40 years

• BMI > 20

• Breasts asymmetry (including tuberous breasts deformity) with indications for treatment with autologous fat grafting

• ASA PS I

Exclusion Criteria:

• Asthma

• A history of allergic reaction to NAC

• Peptic ulcer disease

• Contraindications to MRI imaging

• A history of breast surgery or radiotherapy

• A history of hip/thigh surgery or injury

• Breastfeeding, pregnancy or planned pregnancy within a year

• Ilness or general state of health precluding general anesthesia