Overview

The Impact of Statin Holiday in Dialysis Patients Over 70 Years Old on Mental Function, Physical Function and Frailty

Status:
Unknown status

Trial end date:
2021-05-01

Target enrollment:

Participant gender:

Summary

Patients who are on chronic dialysis and 70 and older are frequently on multiple medications including statins. However, the benefit of statins in dialysis patient population is uncertain. Several randomized trials showed no benefit of statins on mortality in dialysis patient population. Guidelines recommend not starting statins in patients on dialysis who are not already taking them. However, there are no guidelines on what to do in patients who are already taking statins. The investigators are doing a short pilot study to discontinue statin in our dialysis patient population and evaluating the effects on discontinuation of statins on quality of life, cognition, as physical strength.

Phase:

Phase 4

Details

Lead Sponsor:

Loyola University

Treatments:

Hydroxymethylglutaryl-CoA Reductase Inhibitors