The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria
Status:
Completed
Trial end date:
2015-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the feasibility of the scale-up of sulphadoxine-
pyrimethamine (SP) for the preventive treatment of malaria in pregnancy in three Local
Government Areas (LGAs) in Sokoto State, Nigeria. The scale-up strategy tested included the
introduction of community-based distribution of SP in addition to ongoing health facility
distribution during antenatal care (ANC) visits. In addition, the study examined for the
effect of SP use by participants during pregnancy on the head circumference of live newborns
and on the odds of a baby being a stillborn. Finally, the investigators also sought to
quantify the costs associated with program scale up SP to deliver at least three doses of SP
per participant via a government operated distribution program.
Phase:
N/A
Details
Lead Sponsor:
JSI Research & Training Institute, Inc.
Collaborators:
Bill and Melinda Gates Foundation Federal Ministry of Health, Nigeria
Treatments:
Fanasil, pyrimethamine drug combination Pyrimethamine Sulfadoxine