The Influence of AMH on Ovarian Responsiveness to Ovulation Induction With GnRH in Women With PCOS

• Status: Unknown status
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

The investigator suggests that PCOS women with high AMH levels are resistant to ovarian stimulation and may need adjustment of the dose of gonadotrophin.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams Maternity Hospital
• Treatments: Triptorelin Pamoate

Criteria

Inclusion Criteria:

• Women of age 18 - 35 years

• BMI 20 - 30 kg/m2

• Anovulatory infertility

• Diagnosis of PCOS based on Rotterdam consensus criteria (two of three criteria:

Oligo/anovulation, hyperandrogenaemia and sonographic appearance of polycystic ovaries)

Exclusion Criteria:

• Women Above 35 years or under 18 years

• Women with BMI above 30 kg/m2 or under 20 kg/m2

• Normally ovulating women

• Patients with marked hyperandrogenaemia were screened for congenital adrenal hyperplasia (by measuring serum concentration of 17alpha hydroxyl-progesterone) or Patients with Cushing syndrome (by measuring urinary free cortisol)