The Influence of Hyaluronic Acid Injection Following Knee Arthroscopy

• Status: Unknown status
• Trial end date: 2018-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective, double blind randomized controlled trial. In this study we will investigate the influence of hyaluronic acid injection to knee after knee arthroscopy, when known or discovered cartilage damage greater than International Cartilage Research Society score (ICRS) grade 2 is found. The indication for arthroscopy is not necessarily the cartilage damage. A set of 3 consecutive injections will be administered and follow up of physical examination and questionaries will be done.

Our null hypothesis is that the administration of hyaluronic acid will show decrease pain and quicker rehabilitation and return to normal activity in patients with grade 2 and higher cartilage damage that had gone through knee arthroscopy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ziv Medical Center
• Treatments: Hyaluronic Acid; Polystyrene sulfonic acid

Criteria

Inclusion Criteria:

• 18 years old

• signing a concent form

• Assigned for knee arthroscopy.

• Known chondral lesion of at least ICRS grade 2 in one or mor of the knee compartments per MRI prior to knee arthroscopy.

• Cartilage lesion of at least ICRS grade 2 in one or mor of the knee compartments that was found during the knee arthroscopy.

Exclusion Criteria:

• Rheumatic disease

• Synovial disease such as (but not limited to) Pigmented ViloNodular synovitis (PVNS)

• Infection of the operated knee - new or previous

• Pregnant women.