The Influence of Inhaled Adrenalin Versus Decongestant as a Local Nasal Treatment in Bronchiolitis
Status:
Completed
Trial end date:
2005-03-01
Target enrollment:
Participant gender:
Summary
This was a randomized, double blinded, controlled trial. The aim of the study was to compare
xylometazoline HCL nasal drops to inhalation of epinephrine as a treatment for bronchiolitis.
The study hypothesis is:xylometazoline HCL nasal drops treatment is good as epinephrine
inhalation for treatment of bronchiolitis.
Signed informed consent was obtained from a parent of each child. And the human ethics
committee of our hospital approved the study according to the principles of the Declaration
of Helsinki.(Approved - 2002)
Patients:
65 infants who were admitted to Pediatric A- a general pediatric ward, in Schneider
Children's Medical Center because of bronchiolitis during winter in two consecutive years
2004-2005.
The inclusion criteria were: Full term previously healthy Infants, ages 1-12 months, after
informed consent was signed with clinical presentation of mild to moderate bronchiolitis
according to a clinical score .Exclusion criteria were as follows: prematurity, congenital
lung or cardiac disease, infants who had past hospitalization due to respiratory illness and
severe bronchiolitis (score>7 with a range scale 0-10).