The Influence of Intra-alveolar Application of Honey on Healing Following Extraction

• Status: Unknown status
• Trial end date: 2017-08-01
• Target enrollment: 0
• Participant gender: All

Summary

A prospective randomized parallel trial will be carried out on 100 patients who have extraction of single molar tooth. Teeth extractions will be done under local anesthesia. The patients will be divided randomly into two parallel groups. Group 1: The patients will start using Chlorhexidine mouthwash on the second day of extraction twice daily for 7 days. Group 2: After extraction, Manuka Honey will be applied topically into the extraction socket. Postoperative instructions will be given for all patients in addition to the prescription of ibuprofen 600 mg every 8 hours for 3 days.

Re-evaluation:

Postoperative day 3: tenderness with probing the socket, empty socket, food debris, halitosis and assessment of pain. For group 2, the intra-alveolar application of honey will be repeated. Re-evaluation will be repeated in the seventh post-operative day. Acute alveolar osteitis, (dry socket) is diagnosed if the patient presented between the 2nd and 4th days with pain or tenderness in the socket with probing, empty socket and food debris with or without halitosis.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Riyadh Colleges of Dentistry and Pharmacy
• Treatments: Chlorhexidine; Chlorhexidine gluconate

Criteria

Inclusion criteria:

• Patients who have extraction of single molar tooth

Exclusion criteria:

• Patients with uncontrolled systemic diseases

• Pregnant women

• Breastfeeding women

• Women are using oral contraceptives

• Allergy to chlorhexidine

• Allergy to honey

• Presence of acute infection, cystic lesions

• Traumatic extraction

• Extraction requiring bone reduction

• Extractions lasted more than 30 minutes