The primary objective of the study is to determine the optimal intra-arterial drug treatment
regimen for arterial lumen restoration post cerebral vasospasm following aneurysmal
subarachnoid hemorrhage. The secondary objective is to evaluate clinical outcome at 90 days
post discharge following optimal intra-arterial drug treatment for cerebral vasospasm.
We hypothesize that Intra-arterial (IA) infusion of a combination of multiple vasodilators is
more efficacious than single agent treatment cerebral vasospasm therapy.
All procedures done as a part of this study are standard hospital care procedures done to
treat cerebral vasospasm and all drugs to be used are FDA approved.
Phase:
Phase 4
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston
Collaborators:
Brigham and Women's Hospital Geisinger Clinic Lenox Hill Hospital Mayo Clinic Northwell Health Temple University Thomas Jefferson University University at Buffalo University of Illinois at Chicago University of Michigan Wake Forest University Health Sciences Yale University