The Leukotriene Modifier Or Corticosteroid or Corticosteroid-Salmeterol Trial
Status:
Completed
Trial end date:
2006-08-01
Target enrollment:
Participant gender:
Summary
This research study will compare the treatment effects of three different asthma medications
in asthma subjects whose asthma is well controlled when they take fluticasone, an inhaled
corticosteroid. The treatments are fluticasone, montelukast (an anti?leukotriene drug), and a
combination therapy of fluticasone and salmeterol (a long-acting beta-agonist). Fluticasone,
montelukast, and the combination therapy of fluticasone and salmeterol (Advair DiskusĀ®) are
all approved for the treatment of asthma. We are looking at whether the three treatments are
equally effective for reducing the number and the severity of asthma attacks in subjects with
mild to moderately severe asthma.