The Long Term Effect of Inhaled Hypertonic Saline (6%) in Patients With Non Cystic Fibrosis Bronchiectasis

• Status: Completed
• Trial end date: 2009-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether the daily inhalation of nebulised hypertonic saline (6%) will decrease the incidence of pulmonary exacerbations and increase the quality of life for people with non cystic fibrosis bronchiectasis.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Alfred

Criteria

Inclusion Criteria:

• diagnosis of bronchiectasis on high resolution computer tomography

• at least 2 respiratory exacerbations per year over the past 2 years

• producing sputum daily

• in a stable clinical state

• over 18 years of age.

Exclusion Criteria:

• cystic fibrosis

• Positive response to hypertonic saline challenge - FEV 1 decreased by ≥ 15%

• FEV 1 ≤ 1L