The purpose of this study is to develop a new protocol using two different types of fertility
drugs that is more similar to the way the hormones act in a normal menstrual cycle (period).
We are recruiting women who are trying to get pregnant through In Vitro Fertilization (IVF)
who either have a high prolactin level (a hormone normally found in your blood that is
produced in the brain) or have a condition known as hypothalamic amenorrhea in which one does
not get regular periods due to low hormone levels.
The ovaries can be stimulated with Follicle Stimulating Hormone (FSH) alone and with FSH and
Luteinizing Hormone (LH). FSH causes eggs to be made while LH causes estrogen (hormone)
production. The women in this study have low hormone levels and need both FSH and LH.
Luveris® (LH hormone) is a new drug approved for egg production and is used in IVF. There is
no set amount of LH nor a set protocol for LH use. Therefore, we are testing this new
regimen. One group of women will receive a fixed dose of LH throughout their cycle while the
other will decrease the dose of FSH while at the same time increasing the LH dose which is
what happens in the natural menstrual cycle.