The MASTER Study (MAmmary Cancer STatin ER Positive Study)
Status:
Recruiting
Trial end date:
2035-01-01
Target enrollment:
Participant gender:
Summary
Given the compelling evidence supporting a protective effect of statins on breast cancer
recurrence, calls for prospective clinical trials have been expressed. In this trial - the
MASTER trial - we hypothesize that the addition of statin treatment to the current breast
cancer treatment will improve the prognosis of women with early breast cancer. This trial is
designed as follows: a randomized, multicenter, double-blind, placebo-controlled comparison
of standard (neo)adjuvant therapy plus placebo versus standard (neo)adjuvant therapy plus
atorvastatin in patients with early breast cancer.
Phase:
Phase 3
Details
Lead Sponsor:
Aarhus University Hospital
Collaborators:
Aalborg University Hospital Bornholms Hospital Herning Hospital Hospital of Southern Jutland Naestved Hospital Nordsjaellands Hospital Odense University Hospital Rigshospitalet, Denmark Sygehus Sønderjylland University of Copenhagen Vejle Hospital