The Management of Systemic-Pulmonary Collateral Blood Flow in Cyanotic Children During Cardiopulmonary Bypass - Pilot Study

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine whether it is possible to manage the flow of blood through blood vessels using varying levels of carbon dioxide during cardiac surgery, and what effect this has on how well the major organs of the body work.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust

Criteria

Inclusion Criteria:

• Patients whose parents/guardians are willing and able to provide written informed consent for participation in the study

• Patients undergoing elective TCPC surgery

• MRI proven presence of MAPCA vessels

• Patients between 1 day and 5 years of age

Exclusion Criteria:

• Emergency surgery

• Documented history of cognitive impairment (may have an effect on biochemical markers of cerebral injury)

• Documented history of major organ dysfunction