The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia

• Status: Terminated
• Trial end date: 2015-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine the ideal dosage of intrathecal morphine for intra and post partum analgesia, while minimizing the side effect profile.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beth Israel Deaconess Medical Center
• Treatments: Morphine; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• singleton pregnancy,

• at least 36 weeks gestational age,

• active labor (≤ 5 cm dilation) requesting neuraxial analgesia,

• ASA I or II,

• not currently taking pain medications.

Exclusion Criteria:

• multiple gestation,

• preterm labor,

• systemic opioids in the past 4 hours,

• chronic pain syndromes,

• chronic opioid use,

• contraindications to regional anesthesia,

• allergies to opioids,

• significant co existing medical problems,

• severe pregnancy induced hypertension,

• sedatives,

• magnesium therapy,

• diabetes type 1.