Overview

The Outcome of Treatment of Traumatised Refugees With Psychotherapy and/or Antidepressants

Status:
Completed

Trial end date:
2014-04-01

Target enrollment:
0

Participant gender:
All

Summary

The purpose of the study is to investigate the effect of treatment of traumatized refugees with a diagnosis of Post-Traumatic Stress Disorder (PTSD). The existing evidence point towards antidepressants of the type SSRI and trauma-focused cognitive Behavioural Therapy being the most effective treatments of PTSD, but very little evidence of treatment effects exist for the group of multitraumatized refugees. This study therefore seeks to investigate the treatment effect of 6 months drug therapy with antidepressants (Sertraline and/ or Mianserine) and/or trauma-focused cognitive behavioral therapy. A total of 200 individual will undergo treatment. They will be randomized to 4 different groups: antidepressants, psychotherapy, a combination og drug and psychotherapy and a waiting list. Outcome measures include symptoms, life quality and function. Patients with a diagnosis of drug abuse or psychosis will not be included. The hypothesis is that a combination of antidepressants and psychotherapy will be more effective than either of the two treatment regimes on their own.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Caecilie Buhmann

Treatments:

Antidepressive Agents
Sertraline

Criteria

Inclusion Criteria:

- Adult traumatised refugee with PTSD

Exclusion Criteria:

- psychosis and drug abuse