Overview

The Prediction of Extent and Risk Profile of Coronary Atherosclerosis and Their Changes During Lipid-lowering Therapy Based on Non-invasive Techniques

Status:
Unknown status

Trial end date:
2015-06-01

Target enrollment:

Participant gender:

Summary

- The prediction of extent and risk profile of coronary atherosclerosis based on clinical evaluation and non-invasive techniques. - Detailed analysis of plaque volume, plaque composition, risk plaque features and shear stress (WSS) changes during lipid lowering therapy (rosuvastatin 40mg) from 3D vessel reconstruction. - Prediction of changes in coronary arteries based on changes in non-invasive examinations. - Examination of WSS influence on atherosclerosis development and changes of WSS during lipid lowering therapy.

Phase:

Phase 4

Details

Lead Sponsor:

General University Hospital, Prague

Collaborators:

Czech Ministry of Education
Loyola University Chicago
Ministry of Health, Czech Republic
University of Iowa

Treatments:

Rosuvastatin Calcium