The Protective Effect of Ginkgo Biloba Extract on Cisplatin-induced Ototoxicity in Humans

• Status: Completed
• Trial end date: 2008-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The proposal of this study was to evaluate in human beings, using distortion product otoacoustic emission (DPOAE) test, the action of ginkgo biloba extract (GBE761)as a possible ear protective against cisplatin (CDDP) induced hearing loss.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Brasilia
• Treatments: Cisplatin

Criteria

Inclusion Criteria:

• Over the age of eighteen

• Patients that will begin treatment with cisplatin

• No prior treatment with cisplatin

Exclusion Criteria:

• Individuals with middle ear, cochlear or retrocochlear disease

• Presence of changes in pure tone audiometry and/or distortion-product otoacoustic emissions