The Relationship Between XinKang-I and Chronic Heart Failure
Status:
Not yet recruiting
Trial end date:
2025-12-31
Target enrollment:
Participant gender:
Summary
Background: Heart failure is the severe and terminal stage of various heart diseases, which
is characterized by high morbidity, mortality and readmission. There are few studies on the
relationship between XinKang-I(XK-I) and chronic heart failure.
Objective: To explore the relationship between XK-I and chronic heart failure.
Methods/design: The trial is a single-center, single-blind, randomized study (1:1). It will
recruit 110 patients with chronic heart failure who syndrome of qi deficiency yang deficiency
and blood stasis. The intervention group will receive not only Western medicine, but also
XK-I. The primary end points will be the changes in oxygen consumption volume of anaerobic
threshold (VO2AT), maximum oxygen volume uptake (VO2max), and 6-minute walking distance after
8 weeks of treatment. Both groups will receive 8 weeks of treatment.
Ethics and dissemination: Ethical approval was granted by Ethics Committee of Dongguan TCM
Hospital. Results will be disseminated via peer-reviewed publications and presentations at
international conferences.