The Renin-Angiotensin System in Essential Hypertension
Status:
Terminated
Trial end date:
2006-10-01
Target enrollment:
Participant gender:
Summary
Although ACE Inhibitors and Angiotensin Receptor Blockers are effective blood pressure
lowering agents, the exact mechanisms by which these agents lower BP are still not fully
understood. This study aims to compare the blood pressure and hormonal responses (plasma
renin activity and aldosterone) to the ACE inhibitor enalapril and ARB candesartan in
individuals with mild essential hypertension.