The Role of COX-2 Inhibition in Salt Sensitivity of Blood Pressure

• Status: Completed
• Trial end date: 2009-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if the drug Celebrex changes the way the kidney gets rid of salt and maintains blood pressure.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Delaware
• Collaborator: Christiana Care Health Services
• Treatments: Celecoxib

Criteria

Inclusion Criteria:

• healthy men and women

Exclusion Criteria:

• history of heart disease

• have had heart surgery

• high blood pressure

• diabetes

• cancer

• any other disease such as kidney or neurological diseases

• taking medications such as aspirin or medicines for your heart or blood pressure

• have asthma or are allergic to sulfa drugs

• body mass index greater than 30

• use tobacco

• pregnant

• women using oral contraceptives or hormone replacement therapy