The Role of Central Serotonergic and Adrenergic Systems in the Effectiveness of DNIC (Diffuse Noxious Inhibitory Control

• Status: Completed
• Trial end date: 2012-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The role of central serotonergic and adrenergic systems in the effectiveness of DNIC (Diffuse Noxious Inhibitory Control) will be tested before and after taking Duloxetine and Placebo in a double blind study.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rambam Health Care Campus
• Treatments: Adrenergic Agents; Duloxetine Hydrochloride

Criteria

Inclusion Criteria:

• Healthy volunteers

• age 18-80

• no chronic disease

Exclusion Criteria:

• Subjects who suffer from chronic pain / pain syndrome

• use of anti-depressant or anti-psychotic drugs

• food/ drugs sensitivity

• breast feeding