The Role of Dendritic Cells in Hepatitis C Infection
Status:
Completed
Trial end date:
2004-12-01
Target enrollment:
Participant gender:
Summary
The role of the dendritic cells, the most potent antigen presenting cells, in the
establishment of chronic hepatitis C is not established. The study aims to define whether the
dendritic cells are affected by the hepatitis C virus and whether that bears an impact on the
antiviral immune response they generate. The hypothesis is explored by investigating a group
of patients prior to and after the initiation of standard treatment for hepatitis C with
pegylated Interferon and Ribavirin.