The Role of Histamine in Muscle Protein Synthesis Following Resistance Training

• Status: Recruiting
• Trial end date: 2026-12-31
• Target enrollment: 0
• Participant gender: Male

Summary

Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses the following research question: "What is the influence of histamine H1 signaling on training adaptations following ten weeks of resistance training in human skeletal muscle." Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Ghent
• Collaborator: Research Foundation Flanders
• Treatments: Fexofenadine

Criteria

Inclusion Criteria:

• Male

• 18-45 years

• Not to medium physically active

Exclusion Criteria:

• Smoking

• Chronic disease

• High blood pressure

• Supplement or medication intake

• Seasonal allergies

• Vegetarian / vegan

• Resistance trained