The Role of Intra-Operative Intracapsular Blocks in Post-Operative Pain Management Following Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2008-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to use a new combination of anesthesia techniques in an attempt to minimize early pain after surgery and improve the patient's ability to participate more fully with physical therapy. Total knee replacement patients who participate will receive the standard anesthesia. This includes a spinal nerve block as well as a femoral nerve block. The study is looking at the added benefits of including an injection of numbing medication (Bupivicaine) to the back of the knee. This injection occurs during surgery. In order to compare the outcomes we will also have a group of patients who will receive a saline injection as opposed to the numbing medication. Patients are randomly assigned to a group. Outcomes are measured up until twenty-four hours following the surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Duke University
• Collaborator: Pfizer

Criteria

Inclusion Criteria:

• The subject is scheduled to undergo elective total knee replacement at Duke University Hospital.

• The subject has signed the written consent form.

Exclusion Criteria:

• Known allergy to ropivacaine or hydromorphone.

• Known history of narcotic abuse or alcohol abuse.

• Known history of chronic pain.

• Known diagnosis of peripheral neuropathy or complex regional pain syndrome.

• Significant impediment to physical therapy participation.

• The surgery is a revision case.

• Patient is undergoing bilateral Total Knee Replacement.