The Role of Minerelocorticoid Receptor on Modulating Aldosterone Production
Status:
Completed
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this research protocol is to determine if the same effects are observed in
vivo in humans using a similar approach. Demonstrating that mineralocorticoid acts on zona
glomerulosa cells to regulate aldosterone production in a short feedback loop would provide
important insight into hormone regulation, and explain variability in pathophysiologic states
such as hypertension and cardiovascular diseases.