The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis

• Status: Unknown status
• Trial end date: 2012-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the investigators study is to evaluate if short-course of ceftriaxone therapy could shorten the clinical courses of severe nontyphoidal Salmonella enterocolitis in children and the excretion of Salmonella in feces.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chang Gung Memorial Hospital
• Treatments: Ceftriaxone

Criteria

Inclusion Criteria:

• Children with suspected severe Salmonella enterocolitis

• defined as those with a high fever (core body temperature ≥ 38.5℃) persisting for longer than 48 hours

• diarrhea with mucous and bloody-tinged stool.

Exclusion Criteria:

• Children with a toxic appearance, severe vomiting and abdominal distension

• suggestive of sepsis or toxic megacolon, those with an increased risk of invasive NTS diseases

• immunosuppressive illnesses

• had taken antibiotics during the 7 days before the visit will be excluded.