Overview

The Role of Skin Sodium Accumulation in Chronic Kidney Disease

Status:
RECRUITING
Trial end date:
2039-12-01
Target enrollment:
Participant gender:
Summary
This project consists of four substudies: a cohort study (A) and a sodium intake intervention (B) and a sodium excretion intervention (C) and a water intervention study (D). The main objective of the cohort study (A) is to investigate the prognostic implications of tissue sodium accumulation in CKD patients. The primary objective of the sodium intervention studies is to study the effect of high and low sodium intake (B) and increased renal sodium excretion (C) on tissue sodium content. The main objective of the water intervention study (D) is to investigate the effect of increased and habitual water intake on tissue sodium content and transepidermal water loss.
Phase:
NA
Details
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Collaborator:
Dutch Kidney Foundation
Treatments:
Hydrochlorothiazide
lercanidipine
Spironolactone