The Role of Synovitis in Osteoarthritis

• Status: Recruiting
• Trial end date: 2020-03-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine whether platelet-rich-plasma (PRP) or HA (hyaluronic acid)injection into synovitis in osteoarthritis(OA) knee can achieve improvement in knee function and reduce synovitis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Taipei Veterans General Hospital, Taiwan
• Treatments: Hyaluronic Acid

Criteria

Inclusion Criteria:

• diagnosed with OA knee according to ACR guideline

1. stiffness less than 30min

2. cracking sound during activity

3. more than 30min pain for last 2 months

4. non-bed ridden patients

5. no structure abnormality

6. synovitis was proved by US

Exclusion Criteria:

1. OA knee secondary to other disease 2 . more than 10 years after diagnosing OA 3. under knee surgery within 3 months 4. autoimmune disease 5. refuses inform/consent process