The Role of Tranexamic Acid in Reducing Post Operative Hand Edema After Hand and Wrist Surgery
Status:
Not yet recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
Hand edema following hand surgery is a common yet devastating side effect that can lead to
early stiffness, prolonged rehabilitation and diminished function. These factors can reduce a
patient's quality of life; mounting to an overall delay in recovery, return to work and daily
activities. Conventional edema therapy includes cryotherapy, external compression, active and
passive exercises and various types of massage. However, there is little evidence to suggest
these modalities are effective. Tranexamic acid (TXA) is an antifibrinolytic that has been
used in surgical disciplines for decades to aid in reducing intraoperative blood loss and
consequent transfusions. Recently, the use of TXA for curbing post-operative edema and
ecchymosis has shown promising results, however, its use in hand surgery has not been
studied.