The Role of the Gut Microbiome in Modulating Physical Abilities in Humans
Status:
Withdrawn
Trial end date:
2024-09-01
Target enrollment:
Participant gender:
Summary
There is a growing body of evidence indicating the significant contribution of the gut
microbiome to host health and disease. Furthermore, it has been shown that exercise may
modify the microbiome composition. The diversity of athletes' gut microbiome was found higher
compared to gender and age-matched controls. However, important mechanistic questions related
to the possible associations between exercise and the human gut microbiome remain unanswered.
In this study, we propose to investigate using advanced state-of-the-art measurements of
physical activity level and related metabolic parameters whether there is a connection
between the microbiome and physical abilities in healthy participants and whether antibiotics
consumption can influence host physical abilities and glycemic responses through changes
induced in microbiome composition and function.