The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
To determine whether cidofovir (HPMPC) therapy administered by intravenous infusion can
extend the time to progression of peripheral cytomegalovirus (CMV) retinitis in AIDS
patients. To evaluate the safety and tolerance of HPMPC therapy when administered by
intravenous infusion in AIDS patients with CMV retinitis that is not immediately
sight-threatening. To evaluate the virologic effects of intravenous HPMPC therapy on CMV
shedding in urine, blood, and/or semen. To evaluate the impact of HPMPC therapy on visual
acuity.